Characterization of cell death induced by NbBPS1 silencing in Nicotiana benthamiana

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Characterization of cell death induced by NbBPS1 silencing in Nicotiana benthamiana.

We previously showed that silencing of NbBPS1 encoding an endoplasmic reticulum (ER)-localized protein results in pleiotrophic developmental defects and cell death in Nicotiana benthamiana [Kang et al. (2008)]. In this study, we investigated the mechanism of the cell death caused by NbBPS1 silencing. Affected leaf cells exhibited morphological markers of programmed cell death (PCD) and accumula...

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Recent findings suggest a pivotal role for mitochondria-associated hexokinase in the regulation of apoptosis in animal cells. In this study, virus-induced gene silencing (VIGS) of a hexokinase-encoding Hxk1 caused necrotic lesions on leaves, abnormal leaf morphology, and retarded plant growth in Nicotiana benthamiana. Hxk1 was associated with the mitochondria, and this association required the ...

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ژورنال

عنوان ژورنال: Molecules and Cells

سال: 2012

ISSN: 1016-8478,0219-1032

DOI: 10.1007/s10059-012-0096-0